About a quarter of a century ago, researchers discovered a product produced by the body in the process of breaking down the amino
acid L-Arginine and used by the body to enhance a variety of functions. The newly discovered substance, a molecule consisting of one atom of nitrogen and one atom of oxygen, was named Nitric Oxide Synthase, or NOS for short. NO, as it came to be known, proved to be one of the basic building blocks in fields as diverse as physiology, immunology, and neuroscience, so much so that it was named “Molecule of the Year” in 1992, perhaps a rather humorous bit of serious science.
Amino acids have always been viewed as the body’s construction corps, but NO takes pride of place for its variety of functions. Basically, NO is a vasodilator, which simply means that it acts to dilate, or expand, the body’s blood vessels, thereby decreasing the force that must be exerted by the heart muscle to pump a given volume of blood. The applications of that one primary function are amazing!

Produced and sold in supplement form, the use of NO can lower blood pressure by expanding the diameter of the blood vessels and thereby improving the flow of
blood, a process which helps to protect the heart while increasing oxygen supply to the body. NO, as in nitroglycerin pills, dramatically and almost immediately eases the pain of heart attack symptoms, so much so that studies now show nitric oxide as a potential tool in the treatment of angina onset.
But that’s just the beginning. The body’s immune system cells can release NO to kill bacteria and viral or parasite-borne infection. NO enhances the bone marrow’s role in producing new blood cells. It helps in the relief of both pain and inflammation, making it a prime weapon in the fight against rheumatism; in fact, Morphine acts in part by producing nitric oxide. NO’s basic vasodilator function makes it an ideal component of medications designed to lengthen and heighten sexual stimulation. It is a transmitting agent for moving messages between nerve cells, and is part of such diverse processes as sleeping, learning, and memory. It plays a part in feeling pain, and possibly depression as well. It stimulates brain activity and suppresses tumor growth, including cancerous tumor growth. NO may even help with diabetes and insulin resistance issues.
Bodybuilders and athletes have discovered nitric oxide, taking it in nutritional supplements such as GlycoCarn which are believed to increase energy, burn fat, and enhance athletic abilities. The vasodilator properties of nitric oxide translate to accelerated muscle growth because the greater blood flow increases the nutrients delivered to the muscles, thereby allowing them to enlarge under the stress of targeted exercise. And since NO suppresses inflammation, it is potentially effective in reducing the aches and pains of weight training workouts.
There are seemingly no negative effects associated with NO – unless, that is, you take it and then don’t work out. You could find yourself restless, energetic, and feeling ‘hyper’, sort of like downing a large energy drink and then trying to take a nap. And don’t mix it with caffeine; the two would work against each other in your body. As you get started, you should start with small doses and learn your body’s reaction, then increase the dosage as you go.


